MND / ALS
A new MND research breakthrough could help shape treatment research and change how scientists understand the disease. Vesalic Limited, an early-stage biotech company focused on neurodegenerative diseases, announced the findings, with RD Research developing the data platform behind the work. The discovery could inform clinical research and speed the development of treatments for people living [...]
The Longitude Prize on ALS is awarding £2 million to 20 of the world’s most promising multidisciplinary teams of innovators using AI to find new drug targets for ALS (amyotrophic lateral sclerosis) – the most common form of MND (motor neurone disease). The Longitude Prize on ALS is a £7.5m global challenge prize designed to [...]
A forthcoming study will test whether statins, a cholesterol drug, could help people with MND live longer. There is no cure for MND, which causes muscle weakness, can lead people to lose the ability to walk and gets worse over time. People with the progressive neurodegenerative disease usually die within three to five years after [...]
Retinal scans could help doctors tell similar brain diseases apart, with research suggesting they may help detect conditions including ALS and Alzheimer's. There is currently no objective diagnostic test for amyotrophic lateral sclerosis, or ALS, a progressive condition that affects the nerve cells controlling movement, or for frontotemporal lobar dementia with TDP-43, known as FTLD-TDP. [...]
A US researcher has made a promising breakthrough in the quest to help people with amyotrophic lateral sclerosis (ALS). In a recent study, University of Missouri’s Smita Saxena showed that a natural molecule called GM1 can reach the brain when it’s wrapped inside a tiny fat-based bubble. In early laboratory testing, this approach helped improve [...]
People living with motor neurone disease in Sussex are receiving increased support and better access to clinical trials following an expansion of local services. The Sussex MND Network has moved to University Hospitals Sussex, bringing it closer to the clinical teams that support patients every day. The trust said the change is improving joined-up care, [...]
The MND Association has trebled its investment in the MND-SMART trial to speed research into treatments for motor neurone disease. The charity has committed £1.5m over five years to the MND-SMART platform, up from £0.5m originally planned. MND Scotland, the founding funder since 2018, remains a partner and will contribute £1m to the £2.5m collaboration. [...]
A musician with MND returned to the stage after AI recreated his singing voice. As reported by the BBC, Patrick Darling, 32, from Bristol, has been a singer and composer since the age of 14 but was diagnosed with the degenerative condition at 29. He described losing the ability to sing and play instruments as [...]
Researchers have grown key brain cells linked to MND and damaged in spinal injuries, opening a path to better disease models and regenerative therapies. The findings lay foundations for disease models and potentially regenerative treatments for conditions including amyotrophic lateral sclerosis (ALS), the most common form of motor neurone disease, and spinal cord injury. Corticospinal [...]
Long-term air pollution may raise the risk of motor neurone disease and worsen outcomes after diagnosis, new research suggests. The study, one of the largest to examine this link, tracked 1,463 people newly diagnosed with MND in Sweden, comparing them with over 7,300 population controls and nearly 1,800 sibling controls to account for genetic and [...]
