Multiple sclerosis
An exercise hormone may ease MS symptoms by protecting nerve cells from damage, early research in mice suggests. Irisin, a hormone released during exercise, appeared to directly shield neurons from damage in a mouse model of multiple sclerosis. An experimental gene therapy raised blood levels of the hormone, reducing clinical disability and limiting nerve cell [...]
MS patients in Wales can face six-hour round trips to England for specialist care, a charity has warned. Research for MS Society Cymru found that a shortage of specialist NHS staff is leading to long waits for treatment. Nearly 7,000 people in Wales live with MS, which affects the central nervous system and can cause [...]
A major trial has found the MS drug ocrelizumab slowed disability progression in primary progressive MS, including older patients and wheelchair users. The international phase III study, a late-stage clinical trial, included more than 1,000 people across 22 countries. It tested ocrelizumab against a placebo, an inactive treatment, in people with primary progressive multiple sclerosis [...]
Spinal cord damage once thought irreversible may be reversible, after researchers grew miniature brain and spinal circuits in the lab. The early-stage research suggests nerve fibres connecting the brain and spinal cord may be able to regrow after damage if key biological signals are targeted. The findings could help scientists understand why paralysis and other [...]
A new report has highlighted urgent gaps in MS diagnosis, symptom relief and treatment of disease progression. The Voice of the Patient report draws on nearly 3,000 survey responses and direct testimony from people affected by multiple sclerosis. Multiple sclerosis, or MS, is a long-term condition affecting the brain and spinal cord. It can cause [...]
Italy’s competition watchdog has opened a probe into Biogen over claims it tried to block access to a cheaper MS drug. The investigation concerns Biogen Italia and its US parent, Biogen, over allegations it tried to prevent rival drugmaker Sandoz from offering a cheaper multiple sclerosis treatment. Italy’s antitrust authority, AGCM, said on Wednesday, May [...]
MS patients face a higher risk of disabling relapses and faster disease progression as access to key treatments varies across the UK, new research has reveaoled. The analysis from the MS Society suggests access to high-efficacy treatments for multiple sclerosis differs significantly depending on where people live. Disease-modifying therapies, known as DMTs, are [...]
A stem cell trial is testing whether transplantation can improve outcomes for people with treatment-resistant relapsing MS. The phase 3 study is comparing autologous haematopoietic stem cell transplantation with the best available therapy for adults whose disease remains active despite previous high-efficacy disease-modifying treatments. Relapsing-remitting multiple sclerosis, or RRMS, is a form of MS where [...]
Psychoactive substances are commonly used by people with multiple sclerosis (MS )and may ease some symptoms while worsening others, a study suggests. MS is a long-term condition affecting the brain and spinal cord that can cause fatigue, pain, mobility issues and other symptoms. Psychoactive substances are drugs or products that affect the brain [...]
An AI partnership aims to find blood-based RNA patterns that could support earlier MS diagnosis and track disease progression. Decode Health and Circular Genomics will work together to analyse circular RNA, stable genetic molecules that may signal disease activity. The companies hope the approach could help doctors diagnose multiple sclerosis earlier and monitor how the [...]
