Multiple sclerosis news
Two companies are collaborating to develop AI-driven MS therapies targeting myelin repair in multiple sclerosis and related disorders. By combining two distinct artificial intelligence platforms, the companies hope to create the first treatment capable of actively restoring the protective myelin coating around nerve fibres, potentially reversing neurological symptoms that current medications cannot address. The collaboration [...]
NICE has recommended natalizumab, sold as Tysabri and Tyruko, as an option for certain people with hard-to-control multiple sclerosis. The decision by the National Institute for Health and Care Excellence will allow NHS coverage of the drug in England, with decisions also influencing NHS coverage in other parts of the UK. The guidance specifically recommends [...]
An MS biomarker linked to disease progression could flag patients most likely to benefit from new drugs, researchers say. The findings were validated in mice and humans and could shape how clinical trials are run for progressive forms of the disease. The study examined “compartmentalised inflammation” (immune activity contained within the brain and spinal cord [...]
Eating more oily fish and wholegrain bread may cut the risk of multiple sclerosis, a study using UK Biobank data suggests. The findings add to evidence that diet is a modifiable factor in preventing the disease. Multiple sclerosis (MS) occurs when the immune system attacks myelin, the protective coating on nerve fibres in the brain [...]
The enzyme CEMIP is tied to myelin damage seen in multiple sclerosis, stroke and Alzheimer's, new research has revealed, pointing to a new target for brain repair. Researchers aim to develop ways to target the enzyme to heal or slow disease. The study, from Oregon Health & Science University, found that cell migration inducing and [...]
A new $1.75 million joint venture will fund and scale breakthrough technologies designed to transform the lives of people living with neurological conditions. The programme, a collaboration between Australian disability services provider MSWA and Founders Factory, will back and fast-track global startups developing cutting-edge solutions, including the use of AI, robotics and wearables that address [...]
A study has identified a shared brain-signalling mechanism in Parkinson’s and Alzheimer’s diseases, revealing a possible common cause behind their neurodegenerative symptoms. Researchers discovered a molecular pathway that disrupts communication between brain cells in both conditions, improving understanding of how their symptoms are produced. The disruption occurs at synapses — junctions between nerve cells where [...]
A biology teacher has become the first UK patient to receive CAR T-cell therapy for multiple sclerosis (MS) as part of a global clinical trial. Emily Henders, 37, received the treatment at University College London Hospital last week after being diagnosed with MS on Christmas Eve 2021. CAR T-cell therapy is tailored for each patient [...]
BioNxt has launched a 15-day dosing optimisation study for its sublingual multiple sclerosis (MS) drug, marking the final step before human bioequivalence testing planned for early 2026. The study represents the last preclinical stage for BNT23001, a thin-film formulation of cladribine designed to dissolve under the tongue for treating MS. Following successful small-animal trials confirming [...]
Having a higher body mass index (BMI) at the time of multiple sclerosis (MS) diagnosis is linked to faster disability progression, particularly when excess weight has been present since early adulthood. A Swedish study of 2,940 people with relapsing forms of MS found that those with persistently elevated BMI – a measure of body fat [...]
