Multiple sclerosis

An MS therapy centre in Wolverhampton has closed until further notice after flash flooding damaged the site. The Wolverhampton Multiple Sclerosis Therapy Centre said the damage happened on 28 August after storms caused flash flooding across the region. The centre will remain closed while the damage is assessed and discussions take place with insurers. [...]

A new oral drug reduced relapses more than established drug teriflunomide in adults with multiple sclerosis in two late-stage clinical trials. Remibrutinib also showed clinically meaningful results in slowing disability progression compared with teriflunomide. Novartis said remibrutinib was well tolerated and showed no liver safety issues, consistent with previous studies. The REMODEL-1 and [...]

Daily step patterns may help track disability in progressive MS and provide a fuller picture of disability than occasional clinic assessments, a study found. Researchers analysing more than two years of data from 529 people found that those with greater disability or walking impairment generally took fewer daily steps. The differences were most pronounced during [...]

A Redditch man plans to cycle the length of the UK without sleeping to raise awareness and funds for the MS Society. Max Williams plans to travel from Land’s End to John O’Groats as the first stage of a wider challenge in which he hopes to cycle through six countries in six months without sleep. [...]

A stroke drug may help preserve and repair myelin damaged by multiple sclerosis, according to a review of animal studies. Nimodipine was also linked to reduced inflammation, nerve damage and disease severity in several of the studies reviewed. Myelin is the protective coating around nerve fibres that is damaged in multiple sclerosis, or MS, disrupting [...]

The FDA has cleared a Phase 2 trial of Lucid-MS, allowing the experimental oral therapy to be tested in people with multiple sclerosis for the first time. The investigational treatment is designed to protect and repair myelin, the fatty sheath surrounding nerve fibres that is damaged in multiple sclerosis. An earlier Phase 1 study involving [...]

People with multiple sclerosis (MS) who take part in structured exercise programmes tend to report lower levels of fatigue, according to an umbrella review. The strongest evidence was found for cardiorespiratory exercise. Resistance training, which often involves weights or resistance bands, was also linked to lower self-reported fatigue, although results varied more between studies. Fatigue [...]

Vitamin C supplements are linked to a lower risk of developing MS, particularly among people with a higher genetic predisposition, a study suggests. The apparent benefit was seen in people with a genetic predisposition to the condition. Researchers stressed that further work is needed to confirm the findings.   MS is marked by [...]

Grey matter damage is linked to a higher risk of worsening disability, cognitive impairment and death in people with multiple sclerosis (MS), a study suggests. The damage was more consistently linked to long-term outcomes than damage to white matter, the other main type of brain tissue. The findings offer new insight into how MRI scans [...]

Scientists have identified a blood marker that could help doctors track the slow, silent progression of multiple sclerosis (MS) and monitor whether treatments are working - even in patients who are not experiencing relapses. The discovery, led by researchers at the University of Basel in Switzerland, focuses on a protein called glial fibrillary acidic protein [...]