Research

The Pentagon is seeking new standards to assess blast-related brain injuries and other causes of mild traumatic brain injury among US military personnel. The initiative aims to establish benchmarks for measuring the physiological and biomechanical effects of blast exposure, including explosions involving enemy munitions and pressure waves produced when personnel fire their own weapons. The [...]

A 12-week intermittent fasting pilot involving 20 people with early-stage Huntington’s disease reported improvements in disease markers without unintended weight loss. Participants followed a time-restricted eating schedule, limiting food intake to a six-to-eight-hour window each day. Researchers observed improvements in measures of disease severity, a blood marker associated with nerve cell damage and cellular energy [...]

A plant compound improved movement and nerve repair in mice with traumatic brain injury, a study has found. The substance, known as isorhoifolin, helped damaged nerve projections regrow and reduced harmful substances in astrocytes, a type of brain cell. Researchers also detected the compound in mouse brain tissue 15 minutes after administering it through the [...]

A trial is testing whether ear-based vagus nerve stimulation can improve hand function and potentially support myelin repair in people with MS. The treatment delivers electrical pulses through the ear during rehabilitation exercises. Researchers are investigating whether it can improve movement by helping the brain adapt and reorganise connections. The study will primarily assess safety [...]

A new blood test sensor could help detect early signs of Parkinson’s disease by measuring three forms of a protein linked to the condition. The technology detects different forms of alpha-synuclein, a protein associated with Parkinson’s, to identify molecular signals in the bloodstream. It can measure these proteins at extremely low concentrations and produce results [...]

Experimental MS therapy Lucid-MS is moving towards phase 2 testing after US regulatory clearance. Quantum Biopharma has entered an agreement with Thermo Fisher Scientific to prepare a clinical trial of the oral therapy in people with progressive multiple sclerosis (MS). The study will assess the safety, tolerability and efficacy of Lucid-MS, which is designed to [...]

A Liverpool neuroscience centre has gained WHO Collaborating Centre status to support international work on brain and mental health. The University of Liverpool's Liverpool Interdisciplinary Neuroscience Centre (LINC) will hold the designation for four years, from June 2026 to June 2030. The appointment places LINC within an international network supporting World Health Organization (WHO) programmes [...]

Traumatic brain injury (TBI) can have lasting effects on the brain's response to stressful situations, new research has found. The study was led by researchers from the Department of Cell Biology, Genetics and Physiology at the University of Malaga, working with Ohio State University's Wexner Medical Center in Columbus, Ohio.   Using animal [...]

A new pill could offer hope to people with Parkinson’s disease after a trial found it reduced symptoms that can impair quality of life. The randomised, double-blind, placebo-controlled study tested Solengepras in people with Parkinson’s across the US, Europe, UK and Australia. Participants received either 75mg or 150mg of solengepras or a placebo while continuing [...]

The National MS Society raised more than US$12m on the first day of a five-year US$1bn campaign to accelerate MS research and expand access to care. The US-based nonprofit launched its Campaign to End MS on 1 October, with nearly 500 guests attending a New York City gala. The organisation said the campaign will support [...]