Dementia

NR Times explores the latest developments in the world of neuro-rehabilitation. Study of killifish reveals how protein dysfunction develops in vertebrate brain cells, shedding light on cognitive decline A new study has shed light on diseases like Alzheimer’s, Parkinson’s, and ALS. Ageing and neurodegeneration are both known to disrupt the production of functional proteins in [...]

People are diagnosed with dementia an average of 3.5 years after symptoms first appear, with early-onset cases facing longer waits of around 4.1 years, new research has foubd. The first global review of dementia diagnosis delays analysed data from 30,257 people in Europe, the US, Australia and China. Delays were longest in younger people and [...]

A new research centre receiving up to £50m over 14 years will develop brain stimulation devices to treat Parkinson’s, dementia, stroke and childhood epilepsy. The Medical Research Council Centre of Research Excellence (CoRE) in Restorative Neural Dynamics will explore how patterns of brain activity relate to behaviour and contribute to neurological disorders. Researchers aim to [...]

Weight loss injections may cut dementia and stroke risk in people with type 2 diabetes and obesity, according to new global research. People taking the drugs were also 30 per cent less likely to die during the follow-up period. Known as GLP agonist drugs, they help regulate blood sugar and appetite by slowing digestion, reducing [...]

A widely used cough medicine may help slow the progression of dementia in people with Parkinson’s disease, new research suggests. The 12-month clinical trial tested Ambroxol – a drug used for decades in Europe to treat respiratory conditions – for its potential to protect brain function in people with Parkinson’s disease dementia. The study included [...]

NR Times explores the latest research developments in the world of neuro rehabilitation. Four key pathways to Alzheimer’s disease mapped by researchers Four distinct pathways that lead to Alzheimer's disease have been identified by researchers, offering new insights into how the condition develops over time rather than from isolated risk factors. The pathways [...]

Good-quality sleep could play a bigger role than sleep duration in protecting brain health in later life, new research suggests. The study monitored women aged 82 and over who had no signs of cognitive impairment. Participants were recruited after experiencing fractures linked to osteoporosis and wore wrist-worn actigraphy devices to track their movement, sleep and [...]

NR Times explores the latest pharma and business developments in business in the world of neuro-rehab. Roche to advance Phase III development for early-stage Parkinson's disease treatment Roche has confirmed it will be advancing to the Phase 3 development of prasinezumab, an investigational anti-alpha-synuclein antibody, in early-stage Parkinson’s disease. Multiple endpoints from the [...]

Cure Parkinson’s and Alzheimer’s Research UK are working on an initiative that could pave the way for innovative neurodegenerative treatments. There is a growing recognition that tackling neurodegenerative diseases could benefit from a collaborative, cross-disease approach.  Cure Parkinson's is recognising the overlap in underlying biological processes and drugs that may show potential therapeutic benefits for [...]

Bacteria in the mouth and gut may contribute to worsening memory and thinking problems in people with Parkinson’s disease, researchers have found. Specific bacterial changes appear to be linked to the progression from mild memory symptoms to dementia – a common and distressing feature of the condition – raising the possibility they could serve as [...]