Multiple sclerosis

Experts are urging tailored strategies to improve diagnosis, treatment and monitoring for older people with multiple sclerosis as care gaps continue. As more people with MS live longer, age-related biological changes increasingly complicate how the condition is diagnosed and managed – yet no universal framework currently addresses these challenges. More than half of people with [...]

Neural stem cell grafts have been shown to regenerate myelin – the protective coating around nerve fibres – in mice with multiple sclerosis (MS)-like brain lesions. Researchers used induced neural stem cells (iNSCs) to test whether these could repair myelin damage in the central nervous system, a key feature of progressive MS. MS is an [...]

Patients in the UK will now have access to a take-home Multiple Sclerosis (MS) tablet - Cladribine - which was previously only prescribed for people with relapsing remitting MS. The disease modifying therapy (DMT) tablet has now been recommended by the National Institute for Health and Care Excellence (NICE). The new recommendation suggests that now, [...]

Now, new research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.  In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. An estimated 90 to 95 per cent of adults [...]

For the first time, researchers have identified that inflammation - long associated with MS - appears to cause increased mutations linked to MS progression. They studied MS brain lesions, visible as spots on MRI scans, which are areas of past or ongoing brain inflammation. Florey Institute associate professor Justin Rubio, head of The Florey’s neurogenetics [...]

Findings from new research could help neurologists in the future prescribe personalised treatment to people living with multiple sclerosis (MS), after scientists studied more than half a million brain cells. Currently, MS treatments target immune cells in the blood, stopping them from reaching the brain and causing damage. These are very effective in the early [...]

People who develop multiple sclerosis (MS) as children and grow up in less advantaged neighbourhoods may have a larger volume of inflammation and brain tissue loss on imaging than those who grow up in more advantaged neighbourhoods, according to a study. MS rarely develops in children. About 5 per cent of people with MS are [...]

Multiple sclerosis (MS) is a debilitating disease of the brain and spinal cord that impacts millions worldwide. In MS, the immune system mistakenly attacks the myelin sheath — a protective layer surrounding nerve cells in the nervous system. The loss of myelin, combined with ongoing inflammation, causes dysfunction and death of nerve cells, making the [...]

New research has identified crucial links between dietary choices and the progression of multiple sclerosis (MS). The study explored how enzymes called ceramide synthase 5 (CerS5) and 6 (CerS6) are responsible for the toxic effect of a palm oil-rich diet on neurons in the central nervous system, which causes a subsequent increase in the severity [...]

Patients in the US with neurological conditions are paying a disproportionate burden in accessing the drug treatments they need, new data suggests. A report published in the American Academy of Neurology's Neurology journal points to soaring out-of-pocket drug costs - the additional costs incurred when sourcing prescriptions such as phone calls to suppliers or delivery [...]