Multiple sclerosis
People who develop multiple sclerosis (MS) as children and grow up in less advantaged neighbourhoods may have a larger volume of inflammation and brain tissue loss on imaging than those who grow up in more advantaged neighbourhoods, according to a study. MS rarely develops in children. About 5 per cent of people with MS are [...]
Multiple sclerosis (MS) is a debilitating disease of the brain and spinal cord that impacts millions worldwide. In MS, the immune system mistakenly attacks the myelin sheath — a protective layer surrounding nerve cells in the nervous system. The loss of myelin, combined with ongoing inflammation, causes dysfunction and death of nerve cells, making the [...]
New research has identified crucial links between dietary choices and the progression of multiple sclerosis (MS). The study explored how enzymes called ceramide synthase 5 (CerS5) and 6 (CerS6) are responsible for the toxic effect of a palm oil-rich diet on neurons in the central nervous system, which causes a subsequent increase in the severity [...]
Patients in the US with neurological conditions are paying a disproportionate burden in accessing the drug treatments they need, new data suggests. A report published in the American Academy of Neurology's Neurology journal points to soaring out-of-pocket drug costs - the additional costs incurred when sourcing prescriptions such as phone calls to suppliers or delivery [...]
A new study has found some cancers to be slightly more frequent in people with multiple sclerosis (MS) than in people without MS. Types of cancers found to have a small increased risk include bladder, brain and cervical cancers. The study does not prove that MS increases a person’s risk of cancer. It only shows [...]
A pioneering new MS treatment which targets neuroimmune pathways will be the focus of a landmark study in the US next year following a breakthrough for its developer. Clinical-stage US-based company SetPoint Medical is developing a platform designed to stimulate the vagus nerve to activate neuroimmune pathways, in turn producing a systemic immune-restorative effect. The [...]
A pioneering study has identified critical biomarkers that can predict disability worsening in MS. The breakthrough research has the potential to transform treatment strategies for millions of MS patients worldwide, paving the way for more personalised and effective treatment plans. The multicentre observational study, presented yesterday at the world's largest MS research congress, ECTRIMS 2024, [...]
A study has revealed significant therapeutic inertia in the treatment of women with multiple sclerosis (MS), highlighting gender disparities that could impact long-term health outcomes for women of childbearing age. The findings suggest that concerns related to pregnancy may lead to delayed or reduced use of disease-modifying treatments (DMTs), even before pregnancy becomes a consideration. [...]
A new study has revealed that the loss of immune regulation seen in Multiple Sclerosis is triggered by an increase in PRDM1-S, a protein involved in immune function, triggering a dynamic interaction of multiple genetic and environmental factors, including high salt uptake. More than two decades ago, a research team in the lab of David [...]
A two-year $96,812 F31 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health has been awarded to study fear of falling in those with multiple sclerosis (MS). The grant was awarded to Taylor Takla, a Ph.D. candidate in the translational neuroscience programme in Wayne [...]
