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Neuro rehab research

Could brain organoids revolutionise neuro research?

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Scientists have developed 3D mini-organs from human foetal brain tissue that self-organise in vitro, presenting new possibilities for neuro research.

These lab-grown organoids open up a brand-new way of studying how the brain develops. They also offer a valuable means to study the development and treatment of diseases related to brain development, including brain tumours.

Scientists use different ways to model the biology of healthy tissue and disease in the lab. These include cell lines, laboratory animals and, since a few years, 3D mini-organs.

These so-called organoids have characteristics and a level of complexity that allows scientists to closely model the functions of an organ in the lab.

Organoids can be formed directly from cells of a tissue. Scientists can also ‘guide’ stem cells – found in embryos or in some adult tissues – to develop into the organ they aim to study.

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