Parkinson’s

  • Historic US Act aims to end Parkinson’s Disease

    The National Plan to End Parkinson’s Act which aims to eliminate Parkinson’s Disease was passed by the Senate, and will now go to Biden to be signed into law. The Dr. Emmanuel Bilirakis and Honorable Jennifer Wexton National Plan to End Parkinson's Act is the first federal legislation dedicated to ending Parkinson’s Disease. Under the [...]

  • New Parkinson’s drug shows positive results in preclinical studies

    IRLAB’s drug mesdopetam has displayed antipsychotic properties in an advanced model of Parkinson’ s disease psychosis (PD-P).

    Discover: - IRLAB's preclinical results from mesdopetam in an advanced preclinical model of PD-P - Mesdopetam's potential as a novel therapeutic in PD-P - The role of the dopamine D3 receptor in PD-P
  • Gait freeze in Parkinson’s linked to sleep disorders – study

    Patients with Parkinson’s disease who experience freezing of gait also have sleep disorders, a new study shows. Researchers have found that Parkinson’s disease patients who experience freezing of gait (a sudden inability to initiate or continue movement, often resulting in a fall) wake up several times during the night, feel sleepy during the day, and [...]

  • New findings point to potential new treatments for Parkinson’s

    New findings could help explain the complexity of Parkinson's disease symptoms and point to potential new treatment pathways.

    A research team at Mount Sinai Hospital has identified a previously unreported neuron type with vulnerability in Parkinson's disease.
  • Rune Labs raises $12m to advance new Parkinson’s technology

    Precision neurology software and data company, Rune Labs has secured a further $12 million to accelerate the adoption if its novel Parkinson's technology.

    This latest round, led by new brain disorder fund, Nexus NeuroTech Ventures, with participation from existing investors, including Eclipse, DigiTx Partners, Moment Ventures and TruVenturo GmbH, brings the total amount raised by the company to over $42 million.
  • ‘World-first’ in wearable tech could revolutionise Parkinson’s treatment

    Researchers at the University of Bristol will use wearable tech to measure symptoms of Parkinson’s Disease to determine the effectivity of a new drug or treatment in clinical trials.

    The Transforming the Objective Real-world measUrement of Symptoms (TORUS) project, has received £6 million in funding from the Engineering & Physical Sciences Research Council to create the capability to monitor patients many times every day autonomously, continuously, objectively in their own home and for months at a time.
  • Contradictory role of neuro disease marker discovered

    Researchers have discovered that a protein called phosphorylated α-synuclein, which is associated with several neurodegenerative diseases such as Parkinson’s and Lewy body dementia, is also involved in the normal processes of how neurons communicate with each other in a healthy brain. Phosphorylation is a process where a phosphate ion is added to a specific amino [...]

  • Hopes raised in hunt for earlier PD diagnosis

    Scientists believe they may be closing in on a breakthrough in pursuit of earlier diagnosis in Parkinson’s.

    In the development of Parkinson’s, the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms.

    But without a test that can detect these changes, it’s difficult to intervene early to more effectively slow disease progression.

    Doctors generally must rely on neurological examination and patients’ medical histories when diagnosing Parkinson’s.

    Once clinical symptoms appear, however, the disease has already wreaked irreversible damage in the brain.

  • Notes from the frontline of the Parkinson’s fight

    Boston University's neuro-rehab centre has published an in-depth account of the work of its volunteers in embracing new Parkinson's approaches, including wearable robotics and music systems that help patients walk faster and farther. We have shared their account below. About three years before he retired, David Campbell noticed something weird happening as he typed. Whenever [...]