Neurons stripped of their identity are hallmark of Alzheimer’s disease, study finds

Researchers at the University of California San Diego have identified new mechanisms in neurons that cause Alzheimer's disease.

In particular, they discovered that changes in the structure of chromatin, the tightly coiled form of DNA, trigger neurons to lose their specialised function and revert to an earlier cell state. This results in the loss of synaptic connections, an effect associated with memory loss and dementia. The study was founded on the question: how do neurons in patients with Alzheimer's disease differ from neurons in healthy individuals?
By |2024-07-04T17:45:58+01:0019 November 2020|Research, News|

Researchers generate a brain cell type crucial to support neural activity

The loss of oligodendrocytes (OLs) - highly specialised cells of the brain that produce myelin, an essential structure enabling an efficient transmission of electrical signals and the support of neural activity - is a frequent condition in patients suffering neurodegenerative diseases.

Researchers of the Department of Cellular Biology, Genetics and Physiology of the University of Malaga (UMA) have succeeded in generating human OLs from pluripotent stem cells derived from patients with nervous system diseases, specifically multiple sclerosis or ALS.
By |2024-07-04T17:45:58+01:0019 November 2020|Research, News|

Drivers warned about speed in effort to tackle leading cause of TBI

Drivers are being urged to reduce their speed on the roads to avoid the potential for crashes - the estimated cause of up to 50 per cent of traumatic brain injuries. 

New research has revealed the extent of the problem of speeding on the UK’s roads, with a third of all drivers admitting having been in a vehicle which has exceeded 100mph.  More than a quarter of men - 28 per cent - said they had driven at such a speed on a public road, compared to 9 per cent of women, with those in the 25 to 34 year old bracket being the most prolific offenders, research from road safety charity Brake has revealed. 
By |2024-07-04T17:45:59+01:0018 November 2020|Brain injury, News|

The stroke survivor turned rehab provider

When Mark Fricker suffered a stroke aged just 32, the lack of access to dedicated rehabilitation inspired him to retrain as a stroke rehab specialist. Here, he shares his inspirational story

Mark Fricker is very matter-of-fact about the impact of his stroke.

I view it as a positive moment in my life,” he says.

By |2024-07-04T17:59:16+01:0018 November 2020|Interviews, Insight, News, Stroke|

Brain injury and stroke course developed to help nurses

A first-of-its-kind course for nurses to enhance their capability in supporting patients recovering from brain injuries and strokes has been developed. 

The online course, which is open to applications from around the world, enables registered nurses to study part-time while continuing their clinical roles, and will enable them to develop integrated brain, body and mind specialist skills, which are urgently needed in neurological rehabilitation.
By |2026-02-11T11:43:50+00:0017 November 2020|Inpatient neuro rehab, Care & services, News|

COVID effects on the brain study searching for participants

Neuroscientists exploring the lasting impacts of COVID-19 on the brain are recruiting participants for a study which has been created to provide answers for healthcare professionals and improved care for millions of patients across the world.

The COVID-19 Brain Study is looking to find 50,000 people globally who received a confirmed positive diagnosis of the virus, in order to answer some of the main questions about the disease’s direct and indirect effects on the brain.

The study, which has been translated into three languages, hopes to break new ground in understanding the neurological impact of COVID-19, which so far remains largely unknown.

By |2024-07-04T17:45:59+01:0017 November 2020|News, Brain injury|

Soccer players’ head injury risk could be reduced with simple adjustments to the ball

Up to 22% of soccer injuries are concussions that can result from players using their heads to direct the ball during a game.

To reduce risk of injury, a new study recommends preventing how hard a ball hits the head by inflating balls to lower pressures and subbing them out when they get wet. A study, conducted by Purdue University engineers, found that inflating balls to pressures on the lower end of ranges enforced by soccer governing bodies such as the NCAA and FIFA could reduce forces associated with potential head injury by about 20%. But if the ball gets too wet, it can quickly surpass the NCAA weight limit for game play and still produce a nasty impact, the researchers said.
By |2024-07-04T17:45:59+01:0017 November 2020|News|

Re-mapping taste in the brain

What happens in our brain that makes us experience the sweet taste of a donut or the bitter taste of tonic water? What are the patterns of neural activity responsible for the perception of taste?

A new study from Stony Brook University found that the map of neural responses mediating taste perception does not involve, as previously believed, specialized groups of neurons in the brain, but rather overlapping and spatially distributed populations. The findings, to be published in Current Biology, counter an influential but controversial theory based on studies suggesting that there is a topographic map in the gustatory cortex that is responsible for our perception of taste. According to this theory, the gustatory cortex has "hot spots" of neurons whose activation leads to the perception of certain tastes. The new study by Stony Brook researchers demonstrates such a simple map of taste does not exist in the cortex of behaving animals.
By |2024-07-04T17:46:00+01:0017 November 2020|Research, News|

Osseointegration for amputees – key considerations in a schedule of loss

Richard Biggs, senior associate at Irwin Mitchell, takes a closer look at the practical benefits and cost issues related to osseointegration.

I have considered for several years as to how to plead a schedule of loss on an amputation case where a Claimant may choose to undergo osseointegration in the future. Osseointegration is described as follows:- (source London International Patient Services):“OsseoIntegration is an operative procedure used to eliminate the need for a conventional socket prosthesis”. Put simply, during osseointegration an implant is attached directly to a patient’s bone and left to protrude through the skin. It offers a rapid connection between the prosthetic limb and the stump and also provides an element of stability for the patient’s long term prosthetic use. In my experience of discussing the issues with patients who have undergone osseointegration in the past they all report that it is a lifechanging experience.
By |2024-07-04T17:46:00+01:0016 November 2020|News, Legal|

Carers at risk of being forgotten

A study has found that 68% of people believe they should ‘reach out’ to carers more often – with 60% of respondents only asking carers how they are ‘now and again’, ‘rarely’ or ‘almost never’; leaving carers at risk of feeling forgotten.

Furthermore, 72% of respondents worried that carers struggled with ‘loneliness’ thanks to the full-on nature of care leaving them little time for socialising. Throughout the pandemic, caregivers have been at the forefront of the fight, looking after the most vulnerable in society and putting their own lives on the line to do so. In light of this, a campaign called #ReachOutAndHelpOut has been launched to encourage support for carers as they continue to deliver essential care to those in need – amidst fears that carers’ wellbeing is often overlooked.
By |2024-07-04T17:46:00+01:0014 November 2020|News, Brain injury|
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