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Use of branched chain amino acids to treat concussion



Use of branched chain amino acids to treat concussion

In a new study, adolescents and young adults with concussion who were treated with branched chain amino acid (BCAA) supplementation showed a significant reduction in total symptom score and faster return to physical activity.

BCAA supplementation has been shown to improve neurocognitive and sleep function in animal models of mild to moderate traumatic brain injury (TBI). 

In a new study published in the Journal of Neurotrauma, researchers set out to determine the efficacy, tolerability, and safety of different doses of oral BCAA supplementation in concussed adolescents and young adults. No serious adverse events were reported. 

Daniel Corwin, MD, Children’s Hospital of Philadelphia, and co-author, stated: “This study provides the first demonstration of efficacy, as well as safety and tolerability of BCAAs in concussed adolescents and young adults – specifically, a dose response effect in reducing concussion symptoms and return to baseline physical activity, in those treated with higher total doses of BCAAs.

“These findings provide important preliminary data to inform a larger trial of BCAA therapy to expedite concussion recovery.”

 David L. Brody, MD, PhD, Editor-in-Chief of Journal of Neurotrauma, added: “My congratulations to the authors. This is an intriguing study that should inspire further research in the field. Many of our patients are interested in the topic of whether there are dietary supplements that may help recovery from concussion, and studies like this one take us closer to answers.”