Parkinson’s
No Doubt guitarist Tom Dumont has revealed his Parkinson's diagnosis after living with early-onset symptoms for a number of years. The musician told fans he is living with early-onset Parkinson's in a video filmed at his home, where he detailed how the disease has affected his life. "I went to my doctor.,I went to a [...]
An early trial suggests a targeted Parkinson’s treatment could safely cut a key protein linked to the disease, though larger studies are still needed. The drug, known as BIIB094, targets LRRK2, the most common genetic contributor to Parkinson’s disease. Variants in LRRK2 are known to increase the risk of developing the neurodegenerative disorder, which affects [...]
Cell therapy has eased Parkinson's motor symptoms in the first few participants in a clinical trial, according to new company data. The data also indicate the treatment appears safe and may restore lost nerve function, according to a company press release. Penelope Hallett, sponsor of the trial and co-director of Mass General Brigham's Neuroregeneration Research [...]
The UK health watchdog is reviewing whether warnings on Parkinson's drugs should be strengthened after links to gambling and sex addictions. The Medicines and Healthcare products Regulatory Agency (MHRA) said it would examine whether more steps are needed to ensure patients have enough information when prescribed the drugs used to treat Parkinson's disease. A group [...]
An oral drug may cut Parkinson’s falls when it reaches the right blood level, according to clinical trial data presented in Europe. Falls are among the most common and serious complications of Parkinson’s, driven by balance and gait problems, and there is currently no satisfactory treatment. The Phase 2b trial tested pirepemat, an [...]
A pesticide used in the US food supply may raise Parkinson’s risk, with research suggesting long-term exposure could increase the chance of the disease. The study compared 829 people with Parkinson’s to 824 people without the disease over a 45-year period, focusing on their proximity to chlorpyrifos, a chemical used on crops including soybeans, fruit [...]
Plastic bottles have been turned into a Parkinson's drug using bacteria, in what researchers say is a first for a neurological disease. Scientists at the University of Edinburgh engineered E. coli bacteria to turn a plastic widely used in food and drink packaging, polyethylene terephthalate, or PET, into L-DOPA, also called levodopa, which is used [...]
A US$6.92m grant from the Michael J. Fox Foundation will help prepare OPM-201 for clinical studies in people with early Parkinson's disease. Oncodesign Precision Medicine has been awarded the research grant to prepare its LRRK2 inhibitor. A Phase 1b trial, along with a Phase 2 study, is expected to start in 2027. The funding follows OPM's [...]
A brain implant detected walking in people with Parkinson's at home with more than 95 per cent accuracy, a study has found. Researchers said the findings could help pave the way for more personalised and responsive therapies for Parkinson's, which is caused by the loss of nerve cells that produce dopamine, a chemical involved in [...]
Microplastics may disrupt brain processes linked to Parkinson's, with a review suggesting pollution could play a part in rising cases. Cases of Parkinson's have doubled over the past 25 years, and researchers said rising levels of plastic pollution in the environment may be partly responsible. The review drew on more than 100 earlier studies, including [...]
