Parkinson’s
A Phase 2a trial of a new Parkinson’s disease drug has passed an interim safety review, allowing researchers to proceed with higher dose testing. The EXIST study is assessing exidavnemab as a potential treatment for Parkinson’s disease and multiple system atrophy (MSA)—a rare disorder where nerve cells in multiple areas of the brain progressively deteriorate. [...]
NR Times explores the latest pharma and business developments in business in the world of neuro-rehab. Roche to advance Phase III development for early-stage Parkinson's disease treatment Roche has confirmed it will be advancing to the Phase 3 development of prasinezumab, an investigational anti-alpha-synuclein antibody, in early-stage Parkinson’s disease. Multiple endpoints from the [...]
Cure Parkinson’s and Alzheimer’s Research UK are working on an initiative that could pave the way for innovative neurodegenerative treatments. There is a growing recognition that tackling neurodegenerative diseases could benefit from a collaborative, cross-disease approach. Cure Parkinson's is recognising the overlap in underlying biological processes and drugs that may show potential therapeutic benefits for [...]
Bacteria in the mouth and gut may contribute to worsening memory and thinking problems in people with Parkinson’s disease, researchers have found. Specific bacterial changes appear to be linked to the progression from mild memory symptoms to dementia – a common and distressing feature of the condition – raising the possibility they could serve as [...]
A new pilot scheme offering grants of up to £3,000 will help more marginalised communities across the UK deliver physical activity sessions for people living with Parkinson’s. The Parkinson's UK pilot focuses on groups and areas where people with Parkinson’s are underrepresented in exercise and physical activity provision. The initiative will run alongside the charity’s [...]
In a new study, researchers show that some cell types in the immune system are activated more in patients who have Parkinson’s. Parkinson’s disease is best known for its effects on the central nervous system. In addition, recent scientific advances generally emphasise the role of the immune system in the presence and development of the [...]
In a new study, researchers show that some cell types in the immune system are activated more in patients who have Parkinson’s. Parkinson’s disease is best known for its effects on the central nervous system. In addition, recent scientific advances generally emphasise the role of the immune system in the presence and development of the [...]
A music conductor in the US has returned to the podium after receiving innovative brain technology that controls his Parkinson's tremors, allowing him to lead his symphony with renewed confidence. Rand Laycock*, 70, was diagnosed with Parkinson’s disease shortly before turning 60 after seeking medical advice for thumb twitching. The retired music teacher has guided [...]
Researchers at KAIST have revealed that RNA editing plays a crucial role in regulating neuroinflammation, a key pathology of Parkinson's disease. Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage. A KAIST research team led by Professor Minee L. Choi from the Department of [...]
A stem cell–based therapy may lead to a new treatment for advanced Parkinson’s disease, according to results from a phase 1 clinical trial. The treatment, initially developed at Memorial Sloan Kettering Cancer Center (MSK), involved creating nerve cells (neurons) derived from embryonic stem cells and transplanting them into the brains of 12 Parkinson’s patients. The [...]
