Research
By combining information from many large datasets, researchers have identified several new potential targets for treating or preventing Alzheimer’s disease. The study revealed genes and cellular pathways that haven’t been linked to Alzheimer’s before, including one involved in DNA repair. Identifying new drug targets is critical because many of the Alzheimer’s drugs that have been [...]
Researchers have developed a blood test that can identify early signs of Alzheimer’s disease by measuring proteins linked to the condition. The new test, known as Penta-Plex Alzheimer’s Disease Capture Sandwich Immunoassay (5ADCSI), detects five biomarkers simultaneously, which is more than existing blood tests and runs on equipment commonly used in many laboratories. Scientists have [...]
Patients and staff at a charity which looks after people with complex mental health needs have taken the ‘Co-production Pledge’ to ensure patients have an equal say in their care. The pledge – which everyone at St Andrew’s Healthcare is being urged to take - has been created as part of the hospital’s Co-production Framework [...]
A new study has compared inflammation and brain stress responses in Long-Covid patients for the first time, with individuals who have fully recovered. The results show that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains. While previous Long-Covid studies have [...]
By Consultant Clinical Neuropsychologist at PJ Care, Estefania Triguero Throughout my 15-year career in neurorehabilitation, understanding a patient as a unique individual has always been key. Whether they have a neurological condition or an acquired brain injury caring for that individual requires a compassionate, holistic and person-centred approach. A patient’s family and friends typically play [...]
Studies suggesting that certain viral infections may influence the onset of Alzheimer's diseases are gaining attention. To learn more, a research team has succeeded in breaking the link between viral infection and Alzheimer's disease using a new treatment candidate. The researchers have identified the association between viral infection and Alzheimer's disease and blocked the connection using [...]
Gene therapy company uniQure recently announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to AMT-130 for the treatment of Huntington’s disease. There are currently no disease-modifying therapies available for Huntington's Disease, highlighting the urgent need for innovation. uniQure has stated that AMT-130's Breakthrough Therapy designation has been granted based on clinical [...]
With the closure of essential therapy providers like the National Bobath Cerebral Palsy Centre, families of children with movement disorders are facing a devastating crisis. Vital specialist services are vanishing due to chronic underfunding, leaving parents scrambling to find the support their children desperately need. Disability charities are under unprecedented strain. With little to no [...]
Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases. As these diseases continue to impose a significant global health burden, the innovative use of mitochondrial gene editing offers a promising avenue to address their underlying causes. The dysfunction of mitochondria, triggered by mutations in mtDNA, is now recognised [...]
Obstructive sleep apnoea, commonly associated with cardiovascular and metabolic diseases, also plays a significant but less recognised role in memory decline, according to a new review. Researchers have reviewed evidence from human and animal studies showing that OSA patients often experience notable memory impairments, particularly in visual and verbal working memory. They report that key [...]
